Fundraising - like any deal - is like playing poker
There's no perfect answer. It's a game of negotiation and understanding the variables.
There's what's in your hand, what's in the river, and what's in the deck
Your product and metrics are what's in your hand. The reactions you're getting from investors are like the river (the cards in the middle of the table), the macro-economic conditions are like the deck in the dealer's hand.
Play each round. Pay close attention. Make the best deal you can.